Activated therapy

Activated therapy is an experimental cancer treatment. In activated cancer therapy, a non-toxic therapeutic becomes cytopathogenic (cell-killing) when activated by an external energy source, including ultrasound or red light. The specific activated therapies are referred to as ultrasound activated cancer therapy (USAT) and photodynamic therapy (PDT). When these therapies are used in combination, it is referred to as the SonneLux protocol or sonodynamic-photodynamic therapy (SPDT).[1]

Emerging activated therapeutics (sensitizers) that are used with the SonneLux Protocol are non-toxic and have great specificity for malignant tissue. When activated, the sensitizers cause destruction to cancer cells only and do not impact healthy tissue. The SonneLux Protocol has received some positive results in mouse, zebra fish studies and clinical trials. Further, the mechanism of tumor cell destruction is necrosis instead of apoptosis. A vaccine-like effect has been noted.[2]

References

  1. ^ Activated Cancer Therapy Using Light and Ultrasound - A Case Series of Sonodynamic Photodynamic Therapy in 115 Patients over a 4 Year Period J.N. Kenyon, R.J. Fuller and T.J. Lewis. Current Drug Therapy, 2009,4.
  2. ^ Toxicity and Cytopathogenic Properties Toward Human Melanoma Cells of Activated Cancer Therapeutics in Zebra Fish. T. J. Lewis. Integrative Cancer Therapy, March 1, 2010; 9(1): 84 - 92.